Free delivery on orders over R750. Earn Skin Spots with each product purchased.

DermExcel DermDefence SPF 50

R569,00

Invisible, quick absorbing protection – with no white cast.

A revolutionary sunscreen that combines very high UV protection with cellular and DNA protection. This formula is fragrance-free and anti-comedogenic. It will not clog your pores. For make-up wearing woman, Dermdefence SPF 50 acts as an excellent primer.

Purchase this product now and earn 285 Skin Spots!

DermExcel DermDefence SPF 50 – PRIMER, MOISTURISER AND SUN PROTECTION IN 1 PRODUCT.

Invisible, quick absorbing protection – with no white cast.

A revolutionary sunscreen that combines very high UV protection with cellular and DNA protection. This formula is fragrance-free and anti-comedogenic. It will not clog your pores. For make-up wearing woman, Dermdefence SPF 50 acts as an excellent primer.

Indications:

  • Sun protection: Protection against UVA, UVB, IRA (infrared light), and blue light.
  • Anti-aging: Help to prevent or minimize photoaging.
  • Anti-oxidation: Help to prevent free radical formation.

Ingredient Focus:

Excessive daily blue light exposure (computers & phones) can trigger inflammation and pigmentation.

  • Vitamin E (tocopherol) protects against blue-light-induced oxidation.

Air pollutants induce severe alterations of the normal functions of lipids, DNA, and proteins in the human skin via oxidative damage, leading to extrinsic skin aging, inflammatory or allergic conditions such as contact dermatitis, atopic dermatitis, psoriasis, acne, and skin cancer.

  • Antioxidants prevent DNA damage through antioxidant activity.
  • Glycerin and Sorbitol defend the skin against harmful polluting agents and protect the cells’ DNA by inhibiting penetration of pollutants on the skin, restoring skin barrier function, and reducing inflammation.

Intense infrared radiation, or heat, is detrimental to the skin. Heat increases the production of melanocyte pigment within the skin. It can therefore worsen melasma and other skin pigmentation concerns. Studies demonstrate that IR and heat exposure induces cutaneous angiogenesis, and inflammatory cellular infiltration disrupts the dermal extracellular matrix by inducing matrix metalloproteinases and altering dermal structural proteins, thereby adding to premature skin aging.

  • Coenzyme Q-10 protects against infrared A radiation. It’s a regenerative antioxidant that reduces oxidation, wrinkle depth, and oxidative DNA damage. It’s antioxidant and coenzyme effects also help prevent cell death.
  • Glycerin and Sorbitol defend the skin against harmful polluting agents and protect the cells’ DNA by inhibiting penetration of pollutants on the skin, restoring skin barrier function, and reducing inflammation.

UVA rays are mainly linked to long-term skin damage such as wrinkles, but they are also thought to play a role in some skin cancers. UVB rays have slightly more energy than UVA rays. They can damage the DNA in skin cells directly and are the primary rays that cause sunburns.

  • Neo Heliopan® HMS and Neo Heliopan® OS protect against UVB. 
  • Neo Heliopan® 357 protects against UVA – It is the most important UVA filter in the world.
  • Tinosorb® S offers highly effective, broad-spectrum UVA and UVB protection.

DermExcel™ takes an easy, effective and affordable approach to evaluation and treatment of the skin. Medical-grade skin care products formulated according to pharmaceutical standards of purity, potency, and stability. All active ingredients, and the concentrations and dosing protocols in which they are used, are supported by data published in the peer-reviewed medical literature. Targeted treatments to improve skin conditions and maintain skin health

Octorylene, Octinoxate, Avobenzone, Homosalate, Tinosorb.

Apply every morning. During extensive sun exposure, reapply as needed.

Aqua, Octyl methoxycinnamate, Butyl methoxydibenzoylmethane, Propylene glycol, Ethylhexyl salicylate, Cetyl alcohol, Glycerine, Sorbitan mono stearate, Polysorbate 20, Bis-ethylhexyloxyphenol, Methoxyphenyl triazine, Homosalate, Squalane, Ubiquinone, Phenoxyethanol, Ethylhexyl glycerine, Tocopherol, Triethanolamine, Dimethicone, Acrylate crosspolymer, Disodium EDTA.

AM.
Sensitivity/allergy to any of the active ingredients. Open Wounds/active infections.
50ml.
Face and/or Body.
All.

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.

Get A Personal
Skin Assessment

Black Friday Sale Now Live

Receive up to 20% off on your next Skin Spot order during our Black Friday Sale.

  • Receive 15% off when spending R3,000 or more.
  • Receive 20% off when spending R5,000 or more.
  • Receive 20% off and a FREE Active Ceuticals Hyaluronic Acid Serum when spending R6,000 or more.

Duration: Sale will go live on Thursday, 27 November at 11:55pm and will end on 1 December 2025 at 5pm.

Terms & Conditions: Orders will be dispatched within 3–14 days after purchase. All orders will include complimentary samples while stocks last. Treatment Kits, which are already reduced, are excluded from the sale. Loyalty points will still be earned on all orders, and existing loyalty points may be redeemed during the Black Friday Sale.